Beilstein J. Org. Chem.2009,5, No. 10, doi:10.3762/bjoc.5.10
microwave irradiation.
Keywords: chemoselective; lipase; microwave irradiation; zeinnumber; Introduction
Microwave assisted enzyme catalysis is a popular developing methodology in the field of green chemistry [1]. Enzymes have gained pivotal importance in the production of fine chemicals, pharmaceuticals
characterized by their skin tolerance, good biologic degradability and low toxicity [20]. They also reduce the zeinnumber, which is equivalent to a better skin tolerance.
Keeping in view the above benefits of hydroxy-substituted aliphatic amides 3a–d, it was thought worthwhile to perform their synthesis using